Upregulation of Heme Oxygenase-1 by Acteoside Through ERK and PI3 K/Akt Pathway Confer Neuroprotection Against Beta-Amyloid-Induced Neurotoxicity

An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

Ken Itoh, Tomoki Chiba, Satoru Takahashi et al. · Biochemical and Biophysical Research Communications · 1997 · 4K citations

Life Sciences, Biochemistry, Molecular Biology +14

Hydrogen peroxide mediates amyloid β protein toxicity

Christian Behl · Cell · 1994 · 2.1K citations

Life Sciences, Biochemistry, Neuroscience +14

Oxidative Damage Is the Earliest Event in Alzheimer Disease

Akihiko Nunomura, George Perry, Gjumrakch Aliev et al. · Journal of Neuropathology & Experimental Neurology · 2001 · 1.9K citations · Full text

Life Sciences, Neurology, Neuroscience +17

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region.

Paolo Moi, Isadora Asunis, Antonio Cao et al. · Proceedings of the National Academy of Sciences · 1994 · 1.6K citations

Life Sciences, Genetics, Molecular Biology +17

Dietary Intake of Antioxidants and Risk of Alzheimer Disease

Marianne J. Engelhart · JAMA · 2002 · 1.1K citations · Full text

Life Sciences, Nutrition, Nutritional Sciences +15