Concepedia

Estimation of potency of HERG channel blockers: Impact of voltage protocol and temperature

Jianan Yao, Xiaoyi Du, Daniel C. Lu, Robert L. Baker, Eric D. Daharsh, Philip Atterson

Journal of Pharmacological and Toxicological Methods · 2005 · 92 citations · 20 references

DOI

Concepts

References

20

Properties of HERG Channels Stably Expressed in HEK 293 Cells Studied at Physiological Temperature

Zhengfeng Zhou, Qiuming Gong, Bin Ye et al. · Biophysical Journal · 1998 · 735 citations · Full text

, , +16

HERG, a Primary Human Ventricular Target of the Nonsedating Antihistamine Terfenadine

Mary Louise Roy, Robert Dumaine, Arthur Brown · Circulation · 1996 · 303 citations

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A mechanism for the proarrhythmic effects of cisapride (Propulsid): high affinity blockade of the human cardiac potassium channel HERG

David Rampe, Mary Louise Roy, Adrienne T. Dennis et al. · FEBS Letters · 1997 · 295 citations

, , +17

Class III Antiarrhythmic Drugs Block HERG, a Human Cardiac Delayed Rectifier K<sup>+</sup>Channel

Peter Spector, Mark Curran, Mark T. Keating et al. · Circulation Research · 1996 · 287 citations

, , +17

A comparison of the receptor binding and HERG channel affinities for a series of antipsychotic drugs

Sathapana Kongsamut, Jiesheng Kang, Xiaoliang Chen et al. · European Journal of Pharmacology · 2002 · 242 citations · Full text

, , +15