Dexamethasone as Treatment in Cerebrovascular Disease. 2. A Controlled Study in Acute Cerebral Infarction

Abstract

Fifty-four patients with acute cerebral infarction were included in a double-blind study to evaluate Decadron® as therapy. When comparison of patients with similar levels of consciousness was made, there was no significant difference between those patients receiving Decadron® and those receiving placebo therapy. Three patients developed gastrointestinal tract bleeding in the placebo group, but there were none in the Decadron®-treated group. There was no good correlation between the clinical state of the patient and the CSF pressure, either on admission or during the 14-day course of the study.