Molecules · 2003 · 23 citations · 14 references
PharmacyChemistrySynthetic Medicinal ChemistryProtecting-group StrategyBenzyl Protecting GroupsBenzyl ProtectionHydroxyl Group ProtectionHydroxyl Protecting GroupsRegioselective DeprotectionRegioselective ProtectionSelective Protection
The regioselective protection of the 4-hydroxyl group of 3,4-dihydroxy-benzaldehyde was accomplished with seven different protecting groups (benzyl, p-methoxybenzyl, o-nitrobenzyl, 2,6-dichlorobenzyl, 3,4-dichlorobenzyl, vinyl and propargyl) in yields ranging between 67-75%.
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B. Kuenburg, L. Czollner, Johannes Fröhlich et al. · Organic Process Research & Development · 1999 · 117 citations