Inhibitory effect of propofol on ketamine‐induced c‐Fos expression in the rat posterior cingulate and retrosplenial cortices is mediated by GABA_A receptor activation

Abstract

These results demonstrate that the inhibitory effect of propofol on ketamine-induced c-Fos expression in the PC/RS is mediated by GABAA receptor activation, and suggests that ketamine-induced psychoneuronal adverse effects may be suppressed by propofol via the activation of GABAA receptors.