Potential neuroprotective flavonoid-based inhibitors of CDK5/p25 from Rhus parviflora

The Protein Data Bank

Helen M. Berman · Nucleic Acids Research · 2000 · 39.8K citations

Life Sciences, Biochemistry, Bioinformatics +10

Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function

Garrett M. Morris, David S. Goodsell, Robert S. Halliday et al. · Journal of Computational Chemistry · 1998 · 10.8K citations

Life Sciences, Bioinformatics, Molecular Biology +17

Development and validation of a genetic algorithm for flexible docking 1 1Edited by F. E. Cohen

Gareth Jones, Peter Willett, Robert C. Glen et al. · Journal of Molecular Biology · 1997 · 6.7K citations

Pharmacy, Bioinformatics, Medicinal Chemistry +14

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

Gentry N. Patrick, Lawrence Zukerberg, Margareta Nikolić et al. · Nature · 1999 · 1.5K citations

Life Sciences, Molecular Genetics, Neuroscience +10

Further development and validation of empirical scoring functions for structure-based binding affinity prediction

Renxiao Wang, Luhua Lai, Shaomeng Wang · Journal of Computer-Aided Molecular Design · 2002 · 1.2K citations · Full text

Pharmacy, Bioinformatics, Medicinal Chemistry +16