Concepedia

Fibroblasts from a leprechaun patient have defects in insulin binding and insulin receptor autophosphorvlation

J. A. Maassen, M. P. Klinkhamer, Gerard C.M. van der Zon, Hetty C. M. Sips, W. Möller, H. M. J. Krans, Dick Lindhout, F. A. Beemer

Diabetologia · 1988 · 23 citations · 17 references

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References

17

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

A Ullrich, Jeffrey R. Bell, E. Y. Chen et al. · Nature · 1985 · 2.3K citations

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Insulin‐like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity.

A. Ullrich, Andrew Gray, Albert W. Tam et al. · The EMBO Journal · 1986 · 1.9K citations · Full text

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Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin.

Chao‐Kai Chou, Thomas J. Dull, David Russell et al. · Journal of Biological Chemistry · 1987 · 649 citations · Full text

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Decreased kinase activity of insulin receptors from adipocytes of non-insulin-dependent diabetic subjects.

Gary R. Freidenberg, Robert R. Henry, Donna Reichart et al. · Journal of Clinical Investigation · 1987 · 232 citations · Full text

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Acute insulin action requires insulin receptor kinase activity: introduction of an inhibitory monoclonal antibody into mammalian cells blocks the rapid effects of insulin.

David O. Morgan, Richard A. Roth · Proceedings of the National Academy of Sciences · 1987 · 222 citations · Full text

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