Concepedia

Expansion of wild type allele rather than back mutation in pfcrt explains the recent recovery of chloroquine sensitivity of Plasmodium falciparum in Malawi

Toshihiro Mita, Akira Kaneko, Jeffery K. Lum, Takahiro Tsukahara, Hideaki Eto, Takatoshi Kobayakawa, Anders Björkman, Kazuyuki Tanabe

Molecular and Biochemical Parasitology · 2004 · 62 citations · 21 references

DOI

Concepts

References

21

Principles of Population Genetics.

R. M. Cormack, Daniel L. Hartl, Andrew G. Clark · Biometrics · 1990 · 5.4K citations

, , +17

Mutations in the P. falciparum Digestive Vacuole Transmembrane Protein PfCRT and Evidence for Their Role in Chloroquine Resistance

David A. Fidock, Takashi Nomura, Angela K. Talley et al. · Molecular Cell · 2000 · 1.5K citations · Full text

, , +12

A Molecular Marker for Chloroquine-Resistant Falciparum Malaria

Abdoulaye Djimdé, O K Doumbo, Joseph F. Cortese et al. · New England Journal of Medicine · 2001 · 1K citations · Full text

, , +17

Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum

Michael B. Reed, Kevin J. Saliba, Sonia R. Caruana et al. · Nature · 2000 · 858 citations

, , +13

Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum

John C. Wootton, Xiaorong Feng, Michael T. Ferdig et al. · Nature · 2002 · 728 citations

, , +16