Visualization of Enantiomers in the Liquid-Crystalline Phase of a Fragmented DNA Solution

Abstract

The use of the liquid-crystalline phase of fragmented DNA solution for enantiomeric differentiation by NMR is reported. The lyotropic cholesteric liquid crystal system formed, orients in a magnetic field and is able to discriminate water soluble enantiomeric mixtures in a simple 2D J-resolved NMR experiment.