Evaluation of AAV-Mediated Expression of Chop2-GFP in the Marmoset Retina

Abstract

The rAAV2-mediated expression of ChR2 was observed in the inner retinal neurons in the marmoset retina through intravitreal delivery. The marmoset could be a valuable nonhuman primate model for developing ChR2-based gene therapy for treating blinding retinal degenerative diseases.