American Journal of Physical Medicine & Rehabilitation · 2001 · 54 citations · 36 references
Health ProfessionsRehabilitation MedicineEvidence-based PracticeGood Clinical PracticeRehabilitationClinical TrialsEvidence-based InterventionsEvidence-based Practice ImplementationMedical EvidencePhysical RehabilitationTranslating Evidence Into PracticeMedical AccountabilityMedical RehabilitationPractice EvidenceRandomized Clinical TrialsRehabilitation AccountabilityRehabilitation Outcome Measurement
The expectations and demands associated with evidence-based practice in medical rehabilitation require the use of research procedures that are practice based and practitioner oriented. Traditional research methods, including randomized clinical trials, are powerful techniques for determining the efficacy of rehabilitation interventions; however, randomized clinical trials have some practical and ethical limitations when applied to many research questions important to the field of medical rehabilitation, and alternative methods are needed to fully examine the effectiveness of treatment techniques for individual patients and to document clinical accountability. This paper examines the use of single-system designs and N of 1 research strategies. The advantages and limitations of single-system methods are described, and examples relevant to the documentation of clinical outcomes in medical rehabilitation are presented.
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Evidence based medicine: an approach to clinical problem-solving
William Rosenberg · BMJ · 1995 · 1.2K citations
Scientific Challenges in the Application of Randomized Trials
Michael S. Kramer · JAMA · 1984 · 181 citations