Pharmacological characterization of a β3-receptor agonist (BRL 37,344) and a partial agonist (CGP 12,177A) in neonatal rat liver plasma membranes

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

Molecular Characterization of the Human β ₃ -Adrenergic Receptor

Laurent J. Emorine, Stéfano Marullo, Marie‐M. BRIEND‐SUTREN et al. · Science · 1989 · 1.1K citations

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Atypical β-adrenoceptor on brown adipocytes as target for anti-obesity drugs

Jonathan R.S. Arch, A. T. Ainsworth, Michael A. Cawthorne et al. · Nature · 1984 · 730 citations

Life Sciences, Endocrinology, Pharmacology +16

A simple direct assay for cyclic amp in plasma and other biological samples using an improved competitive protein binding technique

K.C. Tovey, K. G. Oldham, J.A.M. Whelan · Clinica Chimica Acta · 1974 · 564 citations

Life Sciences, Biochemistry, Molecular Biology +14

An adipose tissue-specific beta-adrenergic receptor. Molecular cloning and down-regulation in obesity.

Patrick Muzzin, J P Revelli, Françoise Kühne et al. · Journal of Biological Chemistry · 1991 · 295 citations · Full text

Life Sciences, Pharmacology, Physiology +17