Concepedia

The effects of lansoprazole on erosive reflux oesophagitis are influenced by CYP2C19 polymorphism

Masashi Kawamura, S. Ohara, Tomoyuki Koike, Katsunori Iijima, J. Suzuki, Shoichi Kayaba, Kenji Noguchi, Shiro Hamada, Mitsunori Noguchi, Tooru Shimosegawa

Alimentary Pharmacology & Therapeutics · 2003 · 101 citations · 36 references

DOI

Abstract

The therapeutic effect of lansoprazole on erosive reflux oesophagitis is influenced by the CYP2C19 genotype status. Therefore, a test of CYP2C19 genotype may be useful for the medical treatment of reflux oesophagitis with lansoprazole.

References

36

Symptomatic Gastroesophageal Reflux as a Risk Factor for Esophageal Adenocarcinoma

Jesper Lagergren, Reinhold Bergström, Anders Lindgren et al. · New England Journal of Medicine · 1999 · 3K citations

Prevalence and clinical spectrum of gastroesophageal reflux: A population-based study in Olmsted County, Minnesota

G. Richard Locke, N. J. Talley, A. R. Zinsmeister et al. · Gastroenterology · 1997 · 2.1K citations · Full text

, , +8

The endoscopic assessment of esophagitis: A progress report on observer agreement

David Armstrong, J R Bennett, A.L. Blum et al. · Gastroenterology · 1996 · 1.1K citations

, , +10

The Incidence of Adenocarcinoma in Columnar-Lined (Barrett's) Esophagus

Alan J. Cameron, Beverly J. Ott, W. Spencer Payne · New England Journal of Medicine · 1985 · 724 citations

Relationships among serum pepsinogen I, serum pepsinogen II, and gastric mucosal histology. A study in relatives of patients with pernicious anemia.

I. Michael Samloff, Kalle Varis, T. Ihamäki et al. · PubMed · 1982 · 512 citations