The relationship between protoporphyrin IX photobleaching during real‐time dermatological methyl‐aminolevulinate photodynamic therapy (MAL‐PDT) and subsequent clinical outcome

Abstract

PpIX photobleaching is indicative of the level of cellular damage PDT treatment will induce and therefore the clinical outcome expected within patients. This study indicated the potential of the commercially available fluorescence imaging system investigated to predict treatment success at the time of light irradiation and in the future it may be possible to employ it to individualise treatment parameters to improve dermatological PDT efficacy/outcome.