Efficient Rhodium-Catalyzed Asymmetric Hydrogenation for the Synthesis of a New Class of<i>N</i>-Aryl β-Amino Acid Derivatives

Abstract

[reaction: see text] N-Aryl beta-amino esters were obtained by asymmetric hydrogenation of a new class of N-aryl beta-enamino esters. High conversions and up to 96.3% ee values were achieved with a Rh-TangPhos catalyst.