A Chiral 1,2-Bisphospholane Ligand with a Novel Structural Motif: Applications in Highly Enantioselective Rh-Catalyzed Hydrogenations

Abstract

TangPhos (1) is a highly efficient and practical ligand for asymmetric hydrogenations. High enantioselectivities and turnover numbers were observed in the Rh-catalyzed hydrogenation of α-(acylamino)acrylic acids and α-arylenamides. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2002/z18637_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.