Macrophages dictate the progression and manifestation of hypertensive heart disease

Wall stress and patterns of hypertrophy in the human left ventricle.

William Grossman, David R. Jones, Lambert P. McLaurin · Journal of Clinical Investigation · 1975 · 2.4K citations · Full text

Heart Failure, Cardiac Anatomy, Cardiovascular Function +17

Embryonic and Adult-Derived Resident Cardiac Macrophages Are Maintained through Distinct Mechanisms at Steady State and during Inflammation

Slava Epelman, Kory J. Lavine, Anna E. Beaudin et al. · Immunity · 2014 · 1.4K citations · Full text

Inflammation, Distinct Mechanisms, Cardiomyopathy +13

Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure

Takafumi Oka, Shungo Hikoso, Osamu Yamaguchi et al. · Nature · 2012 · 1.1K citations

Cell Autophagy, Mitophagy, Heart Failure +11

Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C–dependent buffering mechanism

Agnes Machnik, Wolfgang Neuhofer, Jonathan Jantsch et al. · Nature Medicine · 2009 · 945 citations

Inflammation, Angiogenesis, Signal Transduction +15

CCL2/Monocyte Chemoattractant Protein-1 Regulates Inflammatory Responses Critical to Healing Myocardial Infarcts

Oliver Dewald, Paweł Zymek, Kim Winkelmann et al. · Circulation Research · 2005 · 700 citations