Concepedia

SSR240612 [(2 R)-2-[((3 R)-3-(1,3-Benzodioxol-5-yl)-3-{[(6-methoxy-2-naphthyl)sulfonyl]amino}propanoyl)amino]-3-(4-{[2 R,6 S)-2,6-dimethylpiperidinyl]methyl}phenyl)-N-isopropyl-N-methylpropanamide Hydrochloride], a New Nonpeptide Antagonist of the Bradykinin B1 Receptor: Biochemical and Pharmacological Characterization

Jean Gougat, Bernard Ferrari, Lionel Sarran, Claudine Planchenault, Martine Poncelet, Jeanne Maruani, Richard Alonso, Annie Cudennec, Tiziano Croci, Fabio Guagnini,

Journal of Pharmacology and Experimental Therapeutics · 2004 · 123 citations · 22 references

DOI

Concepts

References

22

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

, , +14

A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man

Gary J. Bennett, Yuanyu Xie · Pain · 1988 · 5.4K citations

, , +17

SOME QUANTITATIVE USES OF DRUG ANTAGONISTS

O. ARUNLAKSHANA, H. O. Schild · British Journal of Pharmacology and Chemotherapy · 1959 · 4K citations · Full text

, , +16

Further evidence for ‘pain-related’ behaviours in a model of unilateral peripheral mononeuropathy

Nadine Attal, F. Jazat, V. Kayser et al. · Pain · 1990 · 506 citations

, , +17

Hypoalgesia and altered inflammatory responses in mice lacking kinin B1 receptors

João Bosco Pesquero, Ronaldo C. Araújo, Paul A. Heppenstall et al. · Proceedings of the National Academy of Sciences · 2000 · 376 citations · Full text

, , +17