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Incidence of Spontaneous Tumors in CD<sup>(R)</sup>-1 HaM/ICR Mice<xref ref-type="fn" rid="FN2">2</xref>
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1971
Year
Ham/lcr MiceImmunologyPathologyExperimental PathologyTumor BiologyOncologySurgical PathologyCancer Cell BiologyConsecutive NecropsiesSpontaneous TumorsCancer ResearchLymphoid NeoplasiaHistopathologyMalignant DiseaseTumor MicroenvironmentTumoral PathologyYoungest Age GroupVeterinary ScienceGeneral PathologyMedicine
In a study of the incidence of spontaneous neoplasms in 1,000 consecutive necropsies of CD(R)-1 HaM/lCR mice, the most common lesions in decreasing order of frequency were lymphoreticular, mammary, and pulmonary tumors, osteogenic sarcomas, hemangiosarcomas, and renal and hepatic tumors. The incidence of tumors per 100 animals rose with increasing age from less than 1/100 mice of the youngest age group to 50/100 in mice over 20 months of age.