Omeprazole improves the anti‐obesity and antidiabetic effects of exendin‐4 in <i>db/db</i> mice (奥美拉唑改善唾液素‐4 对<i>db/db</i>小鼠的减肥与降糖作用)*

Abstract

Combined treatment with omeprazole with exendin-4 reduces food intake and body weight gain, most likely through changes in plasma ghrelin and leptin levels, and improves pancreatic insulin and glucagon content by improving glucokinase activity.