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Invasion and Metastasis of a Xenogeneic Tumor in Nude Mice2
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1976
Year
PathologyCancer BiologyTumor BiologyNude MouseMalignant Hamster TumorTumor HeterogeneityCancer Cell BiologyXenogeneic TumorRadiation OncologyCancer ResearchHealth SciencesKnockout MouseXenotransplantationMedicineMalignant DiseaseCell BiologyTumor MicroenvironmentRapid GrowthOncology
When aliquots of a malignant hamster tumor were transplanted to nude mice and to hamsters, the tumor showed 1) more rapid growth in the hamster, 2) local invasion and metastasis in both species, and 3) occasional spontaneous regression in the nude mouse.