Concepedia

RG 12915: a potent 5-hydroxytryptamine-3 antagonist that is an orally effective inhibitor of cytotoxic drug-induced emesis in the ferret and dog.

Leo R. Fitzpatrick, Richard Lambert, Charles Pendley, G.E. Martin, Jeffrey S. Bostwick, George Gessner, John Airey, Raymond D. Youssefyeh, Robert G. Pendleton, Dennis L. Decktor

Journal of Pharmacology and Experimental Therapeutics · 1990 · 24 citations · 0 references

Concepts

MedicinePharmacologyVeterinary PharmacologyCancer PharmacologyChemotherapyPharmacodynamicsCytotoxic ChemotherapyVeterinary ChemotherapyVeterinary Neuropharmacology5-Hydroxytryptamine 3 Receptor Antagonists5-Hydroxytryptamine Receptor PharmacologyAcute EmesisAnimal Disease ModelsAnticancer ChemotherapyAntineoplastic Drug TherapyEmesis Mechanisms