Warfarin and Heparin-Induced Skin Necrosis and the Purple Toe Syndrome: Infrequent Complications of Anticoagulant Treatment

Mutation in blood coagulation factor V associated with resistance to activated protein C

Rogier M. Bertina, Bobby P. C. Koeleman, Ted Koster et al. · Nature · 1994 · 3.8K citations

Medicine, Genetics, Hematology +14

Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C.

Björn Dahlbäck, Martin Carlsson, Peter J. Svensson · Proceedings of the National Academy of Sciences · 1993 · 2K citations

Medicine, Hematology, Clinical Biochemistry +15

The Roles of Protein C and Thrombomodulin in the Regulation of Blood Coagulation

CT Esmon · Journal of Biological Chemistry · 1989 · 1.1K citations · Full text

Medicine, Biochemistry, Molecular Biology +17

Absence of Thrombosis in Subjects with Heterozygous Protein C Deficiency

Joseph P. Miletich, George Broze · New England Journal of Medicine · 1987 · 527 citations

Medicine, Genetics, Hematology +16

The pathophysiology of the prethrombotic state in humans: insights gained from studies using markers of hemostatic system activation

KA Bauer, RD Rosenberg · Blood · 1987 · 394 citations · Full text

Medicine, Hematology, Physiology +13