The role of the sphingosine-1-phosphate signaling pathway in osteocyte mechanotransduction

Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II

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Medicine, Immunology, Nephrology +16

Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens

Ana Olivera, Sarah Spiegel · Nature · 1993 · 895 citations

Life Sciences, Biochemistry, Cell Biology +16

Sensitivity of osteocytes to biomechanical stress in vitro

Jenneke Klein‐Nulend, Arie van der Plas, Cornelis M. Semeins et al. · The FASEB Journal · 1995 · 779 citations

Medicine, Physiology, Biomechanics +16

Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate

Larry Pederson, Ming Ruan, Jennifer J. Westendorf et al. · Proceedings of the National Academy of Sciences · 2008 · 548 citations · Full text

Medicine, Cell Biology, Bone Metabolism +16

Activation of sphingosine kinase 1 by ERK1/2‐mediated phosphorylation

Stuart M. Pitson, Paul A.B. Moretti, Julia R. Zebol et al. · The EMBO Journal · 2003 · 537 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12