Pico liter dispenser with 128 independent nozzles for high throughput biochip fabrication

Abstract

This paper presents the development of the electrostatically driven inkjet-type dispenser for biochip printing. It has 128 independent reservoirs and the same number of nozzles. It is designed based on SEAJet/sup /spl reg// printhead developed for the POS printer. SEAJet/sup /spl reg// technology is suitable for dispensing bio-chemical reagent, because there is no heat generation and no use of harmful material to bio chemical molecules. In addition to the SEAJet/sup /spl reg// fabrication technology, a new process to fabricate micro through-holes and biocompatible polymer coating are developed. The dispenser achieved homogeneous and stable dispensing of protein solution. The typical droplet volume and droplet speed are 15 pico liters and 7 m/sec respectively.