Concepedia

EGFR mutations detected on cytology samples by a centralized laboratory reliably predict response to gefitinib in non–small cell lung carcinoma patients

Umberto Malapelle, Claudio Bellevicine, Caterina De Luca, Maria Salatiello, Alfonso De Stefano, Danilo Rocco, Nicla De Rosa, Fabiana Vitiello, Stefania Russo, Francesco Pepe,

Cancer Cytopathology · 2013 · 80 citations · 20 references

DOIFull text

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Abstract

EGFR mutations detected on cytology specimens by a centralized laboratory can predict TKI treatment response equally well as mutations identified on histology samples.

References

20

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Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma

Tony Mok, Yi‐Long Wu, Sumitra Thongprasert et al. · New England Journal of Medicine · 2009 · 8.2K citations · Full text

<i>EGFR</i> and <i>KRAS</i> mutations in lung carcinoma

Shahreen Billah, John Stewart, Gregg Staerkel et al. · Cancer Cytopathology · 2011 · 225 citations · Full text

Heterogeneous Distribution of <i>EGFR</i> Mutations Is Extremely Rare in Lung Adenocarcinoma

Yasushi Yatabe, Keitaro Matsuo, Tetsuya Mitsudomi · Journal of Clinical Oncology · 2011 · 223 citations

Detection of<i>EGFR</i>Gene Mutation in Lung Cancer by Mutant-Enriched Polymerase Chain Reaction Assay

Hiroaki Asano, Shinichi Toyooka, Masaki Tokumo et al. · Clinical Cancer Research · 2006 · 189 citations