Oral Diseases · 2005 · 16 citations · 23 references
We suggest that PGE2 downregulates IL-1alpha-induced IL-6 production via EP2/EP4 receptors in human PDL cells.
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IL-6 is produced by osteoblasts and induces bone resorption.
Yoshiko Ishimi, Chisato Miyaura, Cheng Jin et al. · The Journal of Immunology · 1990 · 1.1K citations