Analytical Methods · 2015 · 18 citations · 28 references
Life SciencesBiochemistryMolecular BiologyBiosensorsMicrofabricationNucleic Acid BiochemistryMicroscale BiosensorsGold NanostructuresHybridization Detection
Microspotting of HS-PNA strands prehybridized with a complementary DNA strand onto gold surfaces results in PNA layers with excellent hybridization efficiency.
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PNA hybridizes to complementary oligonucleotides obeying the Watson–Crick hydrogen-bonding rules
Ole Buchardt, Leif Christensen, Carsten Behrens et al. · Nature · 1993 · 2.1K citations