miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis - Concepedia

Concepedia

Publication | Open Access

miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis

DOI Full Paper Access

232

Citations

40

References

2010

Year

Michiel Smits, Jonas A. Nilsson, Shahryar E. Mir, Petra M. van der Stoop, Esther Hulleman, Johanna M. Niers, Philip C. De Witt Hamer, Víctor E. Márquez, Jacqueline Cloos, Anna M. Krichevsky,

Abstract

Our results indicate that EZH2 has a versatile function in GBM progression and that its overexpression is at least partly due to decreased miR-101 expression. Inhibition of EZH2 may be a potential therapeutic strategy to target GBM proliferation, migration, and angiogenesis.

References

	Year	Citations

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