International Journal of Pharmaceutical Sciences and Research · 2015 · 654 citations · 39 references
PharmacyOncologyPharmacologyChemotherapyDrug DeliveryDrug DiscoveryCancer NanomedicineMedicinal PlantsNanocarriers For TherapeuticsNanomaterials For Drug DeliveryNanomedicineNanoparticle FormulationsAnticancer ActivityAnticancer ChemotherapyAnticancer Natural ProductsBioactive Plant CompoundsCancer NanotherapyPlant-based TherapeuticsPlant-derived Natural ProductsSecondary Metabolites
Cancer remains a global health burden, driving continuous search for safer therapies and prompting scientific focus on plant‑derived compounds with lower toxicity. This review examines the growing demand for medicinal plant compounds and their properties that make them promising anticancer agents. It highlights emerging nanoparticle‑based nano‑medicine technologies that enhance plant‑derived drug efficacy by controlling release and exploring novel administration routes.
Globally cancer is a disease which severely effects the human population. There is a constant demand for new therapies to treat and prevent this life-threatening disease. Scientific and research interest is drawing its attention towards naturally-derived compounds as they are considered to have less toxic side effects compared to current treatments such as chemotherapy. The Plant Kingdom produces naturally occurring secondary metabolites which are being investigated for their anticancer activities leading to the development of new clinical drugs. With the success of these compounds that have been developed into staple drugs for cancer treatment new technologies are emerging to develop the area further. New technologies include nanoparticles for nano-medicines which aim to enhance anticancer activities of plant-derived drugs by controlling the release of the compound and investigating new methods for administration. This review discusses the demand for naturally-derived compounds from medicinal plants and their properties which make them targets for potential anticancer treatments.
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