Concepedia

ROCK I Has More Accurate Prognostic Value than MET in Predicting Patient Survival in Colorectal Cancer.

Jian Li, Shruthi Bharadwaj, Grace Guzman, Ramana V. Vishnubhotla, Sarah C. Glover

PubMed · 2015 · 11 citations · 14 references

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Abstract

ROCK I provides better efficacy in predicting patient outcomes, compared to either tumor staging or MET expression. As a result, ROCK I may provide a less invasive method of assessing patient prognoses and directing therapeutic interventions.

References

14

Hepatocyte growth factor/<i>c-met</i>signaling pathway is required for efficient liver regeneration and repair

Chang-Goo Huh, Valentina M. Factor, Aranzazu Sánchez et al. · Proceedings of the National Academy of Sciences · 2004 · 736 citations · Full text

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Overexpression and amplification of the met/HGF receptor gene during the progression of colorectal cancer.

Maria Flavia Di Renzo, Martina Olivero, Arianna Giacomini et al. · PubMed · 1995 · 456 citations

, , +16

c-Met is essential for wound healing in the skin

Jolanta Chmielowiec, Malgorzata Borowiak, Markus Morkel et al. · The Journal of Cell Biology · 2007 · 307 citations · Full text

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Up-Regulation of Small GTPases, RhoA and RhoC, Is Associated with Tumor Progression in Ovarian Carcinoma

Akiko Horiuchi, Tsutomu Imai, Cui-ju Wang et al. · Laboratory Investigation · 2003 · 239 citations · Full text

, , +7

Significant association of Rho/ROCK pathway with invasion and metastasis of bladder cancer.

Takao Kamai, T. Tsujii, Kentaro Takagi et al. · PubMed · 2003 · 229 citations