Calycosin inhibits oxidative stress-induced cardiomyocyte apoptosis via activating estrogen receptor-α/β

Estrogen receptor β mediates increased activation of PI3K/Akt signaling and improved myocardial function in female hearts following acute ischemia

Meijing Wang, Yue Wang, Brent R. Weil et al. · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 2009 · 152 citations · Full text

Heart Failure, Cell Death, Female Reproductive Function +21

Calycosin Promotes Angiogenesis Involving Estrogen Receptor and Mitogen-Activated Protein Kinase (MAPK) Signaling Pathway in Zebrafish and HUVEC

Jing Yan Tang, Li Shang, Zhen Hua Li et al. · PLoS ONE · 2010 · 132 citations · Full text

Neuroprotective effect of calycosin on cerebral ischemia and reperfusion injury in rats

Chao Guo, Tong Li, Miaomaio Xi et al. · Journal of Ethnopharmacology · 2012 · 126 citations

Cerebral Ischemia, Health Sciences, Neurophysiology +14

Akt mediates 17β‐estradiol and/or estrogen receptor‐α inhibition of LPS‐induced tumor necresis factor‐α expression and myocardial cell apoptosis by suppressing the JNK1/2‐NFκB pathway

Chung‐Jung Liu, Jeng‐Fan Lo, Chia‐Hua Kuo et al. · Journal of Cellular and Molecular Medicine · 2009 · 97 citations · Full text

Pi3k Sirna, Apoptosis, Immunology +19

Estrogen receptor beta mediates acute myocardial protection following ischemia

Meijing Wang, Paul R. Crisostomo, Troy A. Markel et al. · Surgery · 2008 · 71 citations

Cardiovascular Disease, Hormonal Receptor, Physiology +6