Concepedia

TLR4 and TLR9 are induced in oral lichen planus

Maria Siponen, Joonas H. Kauppila, Ylermi Soini, Tuula Salo

Journal of Oral Pathology and Medicine · 2012 · 37 citations · 27 references

DOI

Abstract

Toll-like receptor 4 and TLR9 are induced in OLP; our finding confirms the results of a previous study. TLR4 and TLR9 may play a part in the pathogenesis of OLP. Further studies are needed to dissect the definitive role of TLRs in OLP pathogenesis and progression and to determine the effect of tacrolimus on the function of TLRs.

References

27

Various human epithelial cells express functional Toll-like receptors, NOD1 and NOD2 to produce anti-microbial peptides, but not proinflammatory cytokines

Akiko Uehara, Yukari Fujimoto, Koichi Fukase et al. · Molecular Immunology · 2007 · 321 citations

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Triggering of Toll-like Receptor 4 Expressed on Human Head and Neck Squamous Cell Carcinoma Promotes Tumor Development and Protects the Tumor from Immune Attack

Mirosław J. Szczepański, Malgorzata Czystowska, Marta Szajnik et al. · Cancer Research · 2009 · 248 citations · Full text

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Toll-like Receptors, NOD1, and NOD2 in Oral Epithelial Cells

Yumiko Sugawara, Akiko Uehara, Yukari Fujimoto et al. · Journal of Dental Research · 2006 · 170 citations

Immunohistochemical localization of Toll‐like receptors 1–10 in periodontitis

Arzu Beklen, Mika Hukkanen, Riina Rautemaa‐Richardson et al. · Oral Microbiology and Immunology · 2008 · 163 citations

Activation of toll‐like receptors 2 and 4 by gram‐negative periodontal bacteria

R. Kikkert, Marja L. Laine, L Aarden et al. · Oral Microbiology and Immunology · 2007 · 161 citations