Compound 48/80 Activates Mast Cell Phospholipase D via Heterotrimeric GTP-Binding Proteins

Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization

William C. Colley, T.-C. Sung, Richard L. Roll et al. · Current Biology · 1997 · 694 citations · Full text

Signal Transduction, Natural Sciences, Molecular Biology +12

Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins).

Tsutomu Higashijima, Sonoko Uzu, Terumi Nakajima et al. · Journal of Biological Chemistry · 1988 · 677 citations · Full text

Gtpase Activity, Toxinology, Mast Cell Disorder +16

Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines. Mechanism and structural determinants of activity.

Tsutomu Higashijima, John P. Burnier, Elliott M. Ross · Journal of Biological Chemistry · 1990 · 602 citations · Full text

Hydrophobic Amines, Peptide Science, Chemical Biology +18

Characterization of Two Alternately Spliced Forms of Phospholipase D1

Scott M. Hammond, John M. Jenco, Shigeru Nakashima et al. · Journal of Biological Chemistry · 1997 · 541 citations · Full text

Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C

Sandra E. Wilkinson, Peter J. Parker, John Nixon · Biochemical Journal · 1993 · 531 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Signal Transduction +15