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Compound 48/80 Activates Mast Cell Phospholipase D via Heterotrimeric GTP-Binding Proteins
90
Citations
32
References
2000
Year
Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization
William C. Colley, T.-C. Sung, Richard L. Roll, +6
Current Biology
Signal TransductionNatural SciencesMolecular BiologyProtein PhosphorylationNovel Regulatory Properties +10
1997
694
Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins).
Tsutomu Higashijima, Sonoko Uzu, Terumi Nakajima, +1
Journal of Biological Chemistry
Gtpase ActivityToxinologyMast Cell DisorderImmunologyMolecular Biology +14
1988
677
Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines. Mechanism and structural determinants of activity.
Tsutomu Higashijima, John P. Burnier, Elliott M. Ross
Hydrophobic AminesPeptide ScienceChemical BiologyCellular PhysiologyTrimeric G Protein +16
1990
602
Characterization of Two Alternately Spliced Forms of Phospholipase D1
Scott M. Hammond, John M. Jenco, Shigeru Nakashima, +7
541
Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C
Sandra E. Wilkinson, Peter J. Parker, John Nixon
Biochemical Journal
Medicinal ChemistryBioorganic ChemistrySignal TransductionBiochemistryProtein Kinase C +13
1993
531
Simultaneous inhibitions of inositol phospholipid breakdown, arachidonic acid release, and histamine secretion in mast cells by islet-activating protein, pertussis toxin. A possible involvement of the toxin-specific substrate in the Ca2+-mobilizing receptor-mediated biosignaling system.
T. Nakamura, M Ui
1985
508
Ca(2+)-dependent and Ca(2+)-independent isozymes of protein kinase C mediate exocytosis in antigen-stimulated rat basophilic RBL-2H3 cells. Reconstitution of secretory responses with Ca2+ and purified isozymes in washed permeabilized cells.
Koichiro Ozawa, Zoltán Szállási, Marcelo G. Kazanietz, +4
Protein SecretionImmunologyWashed Permeabilized CellsCytoskeletonCellular Physiology +14
365
Direct activation of GTP‐binding regulatory proteins (G‐proteins) by substance P and compound 48/80
Marc Mousli, Christian Bronner, Yves Landry, +2
FEBS Letters
299
Interaction of substance P, compound 4880 and mastoparan with the α-subunit C-terminus of G protein
Marc Mousli, Christian Bronner, Joël Bockaert, +2
Immunology Letters
Protein ChemistryMolecular PharmacologyProtein FunctionMolecular PhysiologyBiochemistry +9
179
Activation of the mitogen-activated protein kinase/cytosolic phospholipase A2 pathway in a rat mast cell line. Indications of different pathways for release of arachidonic acid and secretory granules.
Noriyasu Hirasawa, Francesca Santini, Michael A. Beaven
The Journal of Immunology
Cellular PhysiologyInflammationSignaling PathwayReceptor Tyrosine KinaseSecretory Granules +17
1995
170
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