The Relationship Between the Disposition and Immunogenicity of Sulfamethoxazole in the Rat

Differences in Metabolism of Sulfonamides Predisposing to Idiosyncratic Toxicity

Neil H. Shear · Annals of Internal Medicine · 1986 · 375 citations

Activation of drug-specific CD4+ and CD8+ T cells in individuals allergic to sulfonamides, phenytoin, and carbamazepine

D Mauri-Hellweg, Florence Bettens, Davide Mauri et al. · The Journal of Immunology · 1995 · 348 citations

Diagnosis of Sulfonamide Hypersensitivity Reactions by In-Vitro "Rechallenge" with Hydroxylamine Metabolites

Michael Rieder, Jack Uetrecht, Neil H. Shear et al. · Annals of Internal Medicine · 1989 · 240 citations

Prominence of slow acetylator phenotype among patients with sulfonamide hypersensitivity reactions

Michael Rieder, Neil H. Shear, Allan Kanee et al. · Clinical Pharmacology & Therapeutics · 1991 · 217 citations

Adverse Reactions to Trimethoprim-Sulfamethoxazole in Hospitalized Patients

Hershel Jick · Clinical Infectious Diseases · 1982 · 189 citations

Drug Safety, Drug Hypersensitivity, Serious Toxicity +15