Recent Advances of α‐Isothiocyanato Compounds in the Catalytic Asymmetric Reaction

Abstract

Abstract α‐Isothiocyanato amides, esters and phosphonates have emerged as new types of versatile reagents for various organo‐ and metal‐catalyzed asymmetric cascade reactions, which have attracted increasing interest of many chemists. In this review, recent advances of α‐isothiocyanato compounds for the asymmetric cascade aldol/cyclization, Mannich/cyclization, Michael/cyclization, diverse [3+2] cyclization, and self‐cyclization/addition reactions are summarized and classified according to the types of acceptors. magnified image