Concepedia

Plasma Nitric Oxide Concentrations and Nitric Oxide Synthase Gene Polymorphisms in Coronary Artery Disease

Yeomin Yoon, Junghan Song, Seung Ho Hong, Jin Q Kim

Clinical Chemistry · 2000 · 219 citations · 18 references

DOIFull text

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Abstract

Plasma NOx was higher in hypertensive CAD patients than in normotensive CAD patients and controls. The E298D polymorphism of the ecNOS gene was associated with increased plasma NOx. Further study is needed to understand the gene expression and enzyme activity of ecNOS and their association with genotypes.

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