Programmed cell death 4 and micro<scp>RNA</scp> 21 inverse expression is maintained in cells and exosomes from ovarian serous carcinoma effusions

Abstract

PDCD4 and miR-21 are involved in OSC oncogenesis. The transfer of miR-21 by exosomes could promote oncogenic transformation in target cells distant from the primary tumor without direct colonization by cancer cells and could be used as a diagnostic tool.