Gastrointestinal Prokinetic Drugs have Different Affinity for the Human Cardiac Human Ether-à-gogo K+ Channel

A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel

Michael C. Sanguinetti, Changan Jiang, Mark Curran et al. · Cell · 1995 · 2.4K citations · Full text

Medicine, Cardiology, Molecular Genetics +16

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

Mark Curran, Igor Splawski, Katherine W. Timothy et al. · Cell · 1995 · 2.3K citations · Full text

Medicine, Genetics, Molecular Genetics +13

Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents.

Michael C. Sanguinetti, Nancy K. Jurkiewicz · The Journal of General Physiology · 1990 · 1.5K citations · Full text

Medicine, Cardiology, Pharmacology +17

Polyethylenimine but Not Cationic Lipids Promotes Transgene Delivery to the Nucleus in Mammalian Cells

H. Pollard, Jean-Serge Rémy, Gildas Loussouarn et al. · Journal of Biological Chemistry · 1998 · 708 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Prucalopride accelerates gastrointestinal and colonic transit in patients with constipation without a rectal evacuation disorder

Ernest P. Bouras, Michael Camilleri, Duane D. Burton et al. · Gastroenterology · 2001 · 308 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +13