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Incidence of post-abortion intra-uterine adhesions evaluated by hysteroscopy—a prospective study
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1993
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Oestrogen TreatmentHysteroscopyFertilityReproductive HealthGynecologyPathologySurgeryUterine PathologyObstetricsPublic HealthInfertilityMaternal ComplicationMaternal HealthPost-abortion Intra-uterine AdhesionsGynecologic SurgeryPostpartum HemorrhageGynecological SurgeryAbortionSharp CurettageMedicine
A prospective study of 147 women who underwent dilatation and sharp curettage for spontaneous first‑trimester abortion performed diagnostic hysteroscopies 4–6 weeks later using CO₂ distension to assess intra‑uterine pathology. Intra‑uterine adhesions were identified in 19 % of patients, with incidence rising to 32 % after three or more abortions, most adhesions being mild but 58 % of those in later‑aborters severe, underscoring the need for preventive treatment and routine hysteroscopic evaluation.
A prospective study was conducted on the incidence of intra-uterine pathology diagnosed by hysteroscopy in 147 women who underwent dilatation and sharp curettage due to spontaneous first trimester abortion. The diagnostic hysteroscopies were performed 4-6 weeks after the miscarriage, using CO2 as medium for uterine distention. In 38 patients (25.9%), uterine pathology was found, of whom 28 patients (19%) had intra-uterine adhesions (IUA). The incidence of IUA following only one abortion was 16.3% (16 out of 98 cases), all were of mild extent and filmy consistency, occupying less than one-quarter of the uterine cavity. The incidence of IUA after two abortions was 14% (3/21) but the incidence after three or more spontaneous abortions was significantly elevated (32%, 9/28), (P < 0.05, chi-square test). In addition, 58% of IUA diagnosed in the latter two groups were of a more severe extent. After a first miscarriage, occurrence of post-abortion IUA was not related to the serum oestrogen concentration on the day of curettage, nor was it related to any of the oestrogen treatment modalities used in this study. Although in most of these cases normal recovery of the endometrium was the rule, the high incidence of IUA diagnosed in this prospective study stresses the need for preventive treatment and close follow-up of patients after sharp curettage due to spontaneous abortion. Obviously oestrogen treatment alone did not prove to be effective and other treatment methods should be evaluated. The high incidence and severity of IUA in habitual aborters clearly justifies the performance of a diagnostic hysteroscopy as a standard evaluation.