A study on tuberculosis in buffaloes: some epidemiological aspects, along with haematological and serum protein changes

Abstract

The study was conducted to ascertain the epidemiology, together with effects of bovine tuberculosis, on certain haematological parameters and serum proteins at two Livestock Experiment Stations in Pakistan. The results on prevalence of tuberculosis in buffaloes on the basis of comparative intradermal tuberculin test revealed it to be from as high as 8.48% (14/165) to as low as 2.45% (4/163) on the basis of positive reaction to bovine PPD. However, a doubtful reaction was observed in 8.58% (14/163) of buffaloes at farm 2 with low prevalence. It was also observed that the reaction to bovine or avian PPD was much stronger in buffaloes compared with indigenous cattle. The result on certain epidemiological factors studies revealed higher positive reactors of greater than 6 years of age and the majority were between 6-8 years old (P = 0.03). Results also revealed that a significantly higher number of animals had a body mass of less than 550 kg (P = 0.005), had less than three parturitions (P = 0.001) and milk production of 5-7 litres. The number of animals present at the farm, number of species, the nearby village, etc., played a significant role in the prevalence of the disease, rather than the condition of the farm. The results on haematological studies revealed a considerable decrease in RBC, while the decrease in ESR in a significantly (P = 0.05) greater number of buffaloes showed a positive or doubtful reaction to mammalian PPD. Total leukocyte count and lymphocyte percentages were higher in a considerably greater number of buffaloes. However, while changes in monocyte and eosinophil count were less significant, combined monocyte count in both positive and doubtful reactors was higher in a considerable number of buffaloes. While the results on serum proteins revealed an increase in serum total proteins and globulins in a significantly greater number of buffaloes, they had a positive reaction to mammalian PPD. A significant, positive relationship of serum total proteins with globulins in positive (r = 0.918; P = 0.0001) and doubtful reactors (r = 0.691; P = 0.0015).