Dopamine <scp>D</scp>₁ and corticotrophin‐releasing hormone type‐2<scp>α</scp> receptors assemble into functionally interacting complexes in living cells

Abstract

D1 and CRF2 α receptors are capable of heterodimerization in living cells. D1 /CRF2 α receptor heteromerization might account, at least in part, for the complex physiological interactions established between dopamine and CRH in normal and pathological conditions such as addiction, representing a new potential pharmacological target.