Thermodynamics of biological synthesis and growth.

The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-kappa B by targeting the I kappa B kinase complex.

Steffen P. Hehner, Thomas G. Hofmann, Wulf Dröge et al. · PubMed · 1999 · 386 citations

Life Sciences, Molecular Biology, Pharmacology +17

Retinoic acid induced mitogen-activated protein (MAP)/extracellular signal-regulated kinase (ERK) kinase-dependent MAP kinase activation needed to elicit HL-60 cell differentiation and growth arrest.

Andrew Yen, Mark S. Roberson, Susi Varvayanis et al. · PubMed · 1998 · 260 citations

Life Sciences, Cell Biology, Oncology +17

Carnosic acid potentiates the antioxidant and prodifferentiation effects of 1alpha,25-dihydroxyvitamin D3 in leukemia cells but does not promote elevation of basal levels of intracellular calcium.

Michael Danilenko, Qing Wang, Xuening Wang et al. · PubMed · 2003 · 101 citations

Medicine, Oncology, Pharmacology +17

Combinations of retinoic acid with either sodium butyrate, dimethyl sulfoxide, or hexamethylene bisacetamide synergistically induce differentiation of the human myeloid leukemia cell line HL60.

T. R. Breitman, Rui He · PubMed · 1990 · 85 citations

Medicine, Oncology, Pharmacology +9

The NF-kappaB transcription factor in oncogenesis.

H W Sharma, Ramaswamy Narayanan · PubMed · 1996 · 78 citations

Life Sciences, Cancer Biology, Oncology +13