Pharmacology of novel small-molecule tubulin inhibitors in glioblastoma cells with enhanced EGFR signalling

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Nature · 2008 · 7.8K citations · Full text

Medicine, Molecular Genetics, Oncology +12

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

Roel G.W. Verhaak, Katherine A. Hoadley, Elizabeth Purdom et al. · Cancer Cell · 2010 · 7.7K citations · Full text

Medicine, Molecular Genetics, Oncology +12

The Somatic Genomic Landscape of Glioblastoma

Cameron Brennan, Roel G.W. Verhaak, Aaron McKenna et al. · Cell · 2013 · 5.2K citations · Full text

Medicine, Genetics, Molecular Genetics +12

Glioma Stem Cell Lines Expanded in Adherent Culture Have Tumor-Specific Phenotypes and Are Suitable for Chemical and Genetic Screens

Steven M. Pollard, Koichi Yoshikawa, Ian D. Clarke et al. · Cell stem cell · 2009 · 1.1K citations · Full text

Medicine, Cell Biology, Oncology +15

Moving beyond Rules: The Development of a Central Nervous System Multiparameter Optimization (CNS MPO) Approach To Enable Alignment of Druglike Properties

Travis T. Wager, Xinjun Hou, Patrick R. Verhoest et al. · ACS Chemical Neuroscience · 2010 · 1K citations

Pharmacy, Medicinal Chemistry, Pharmacology +17