Concepedia

A mutation in the insulin receptor gene that impairs transport of the receptor to the plasma membrane and causes insulin‐resistant diabetes.

Domenico Accili, C. Frapier, Luitgard Mosthaf, C McKeon, Steven C. Elbein, M. Alan Permutt, Edward Ramos, Eric S. Lander, A. Ullrich, Simeon I. Taylor

The EMBO Journal · 1989 · 155 citations · 46 references

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Concepts

References

46

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.3K citations · Full text

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Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

Randall K. Saiki, David H. Gelfand, Susanne Stoffel et al. · Science · 1988 · 17.2K citations

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Efficient<i>in vitro</i>synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

Douglas A. Melton, Paul A. Krieg, Michael R. Rebagliati et al. · Nucleic Acids Research · 1984 · 6.4K citations · Full text

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A simple and very efficient method for generating cDNA libraries

Ueli Gubler, Beth J. Hoffman · Gene · 1983 · 4.6K citations

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Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

Julian Downward, Yosef Yarden, E. L. V. Mayes et al. · Nature · 1984 · 2.5K citations · Full text

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