Miniature 3D Gas Chromatography Columns with Integrated Fluidic Connectors Using High-resolution Stereolithography Fabrication

Abstract

In this manuscript we report on design, fabrication, and characterization of miniature gas chromatography columns with arbitrary 3D geometry and integrated connectors as separation elements for a mobile ethylene sensor system. In contrast to planar microfabrication, these columns have been realized in a single step additive manufacturing process using high-resolution stereolithography printing. This maskless technology enables the combination of freeform 3D microstructures with packaging aspects in one bulk element. For applications in food monitoring, the columns were packed with Carbosieve®-SII particles as adsorbents. With the printed columns a minimal gas concentration of 35 ppb (3σ) ethylene can be detected. Retention times of 400 s for ethylene and 1035 s for water and no signal peak overlap show an improved separation capability.