Involvement of p21ras distinguishes positive and negative selection in thymocytes.

T cell receptor antagonist peptides induce positive selection

Kristin A. Hogquist, Stephen C. Jameson, William R. Heath et al. · Cell · 1994 · 2.8K citations

T-regulatory Cell, Immunology, Positive Selection +7

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

Paweł Kisielow, Horst Blüthmann, Uwe D. Staerz et al. · Nature · 1988 · 1.7K citations · Full text

Lymphocyte Development, Immunology, Autoimmunity +7

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

Fiona Harding, James G. McArthur, Jane A. Gross et al. · Nature · 1992 · 1.5K citations

Autoimmune Disease, T-cell Clones, Immunology +10

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

André Veillette, Michael A. Bookman, Eva Horak et al. · Cell · 1988 · 1.4K citations

Signal Transduction, Autoimmune Disease, T-regulatory Cell +9

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

Sean E. Egan, B.W. Giddings, Mary W. Brooks et al. · Nature · 1993 · 1.2K citations

Signal Transduction, Signaling Pathway, G Protein-coupled Receptor +8