Concepedia

The glucocerobrosidase E326K variant predisposes to Parkinson's disease, but does not cause Gaucher's disease

Raquel Durán, Niccolò E. Mencacci, Aikaterini V. Angeli, Maryam Shoai, Emma Deas, Henry Houlden, Atul Mehta, Derralynn Hughes, Timothy M. Cox, Patrick Deegan,

Movement Disorders · 2012 · 145 citations · 18 references

DOIFull text

Open access

Abstract

Our results confirm recent reports that the mutation, E326K, predisposes to PD and suggest that, in addition to reduced GBA1 activity, other molecular mechanisms may contribute to the development of the disease.

References

18

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