Concepedia

Expression of hypoxia‐inducible factor‐1α is significantly associated with the progression and prognosis of oral squamous cell carcinomas in Taiwan

Pin‐Yi Lin, Chuan‐Hang Yu, Jeng‐Tzung Wang, Huang‐Hsu Chen, Shih‐Jung Cheng, Mark Yen‐Ping Kuo, Chun‐Pin Chiang

Journal of Oral Pathology and Medicine · 2007 · 90 citations · 38 references

Abstract

We conclude that the expression of HIF-1 alpha is an early event in oral carcinogenesis. The nuclear HIF-1 alpha LI in OSCC samples can predict the progression of OSCCs and the survival of OSCC patients.

References

38

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Donald Maxwell Parkin, Freddie Bray, Jacques Ferlay et al. · CA A Cancer Journal for Clinicians · 2005 · 18.4K citations · Full text

Epidemiology Of Cancer, Worldwide Incidence, Cancer Registration +16

Cancer Statistics, 2005

Ahmedin Jemal, Thomas S. Murray, Elizabeth Ward et al. · CA A Cancer Journal for Clinicians · 2005 · 5.5K citations · Full text

Epidemiology Of Cancer, Cancer Registration, Mortality Rates +16

The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

Katherine Louise Talks, Helen Turley, Kevin C. Gatter et al. · American Journal Of Pathology · 2000 · 1.3K citations · Full text

Inflammation, Tumor Biology, Hypoxia-inducible Factors Hif-1α +12

Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1.

Balaji Krishnamachary, Shannon Berg-Dixon, Brian Kelly et al. · PubMed · 2003 · 630 citations

Tumor Biology, Medicine, Motility Factor +13

Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer.

Peter Birner, Monika Schindl, Andreas Obermair et al. · PubMed · 2000 · 613 citations

Hif-1alpha Expression, Oncology, Cervical Cancer +14