Concepedia

Identification of a new p53/MDM2 inhibitor motif inspired by studies of chlorofusin

Marco M. D. Cominetti, Sarah A. Goffin, Ewan Raffel, Kerrie D. Turner, Jordann C. Ramoutar, Maria A. O’Connell, Lesley A. Howell, Mark Searcey

Bioorganic & Medicinal Chemistry Letters · 2015 · 19 citations · 14 references

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14

Isolation and Structure Elucidation of Chlorofusin, a Novel p53-MDM2 Antagonist from a <i>Fusarium</i> sp.

Sara J. Duncan, Sabine Grüschow, Dudley H. Williams et al. · Journal of the American Chemical Society · 2001 · 171 citations

, , +17

A Versatile Platform to Analyze Low-Affinity and Transient Protein-Protein Interactions in Living Cells in Real Time

Yaocheng Li, Luo Wei Rodewald, Christian Hoppmann et al. · Cell Reports · 2014 · 83 citations · Full text

, , +15

Total Synthesis of Chlorofusin, Its Seven Chromophore Diastereomers, and Key Partial Structures

Ryan C. Clark, Sang Yeul Lee, Dale L. Boger · Journal of the American Chemical Society · 2008 · 65 citations · Full text

, , +17

Total Synthesis, Assignment of Absolute Stereochemistry, and Structural Revision of Chlorofusin

Wen‐Jian Qian, Wanguo Wei, Yongxia Zhang et al. · Journal of the American Chemical Society · 2007 · 49 citations

, , +14

A Fluorescence Polarization Assay for the Identification of Inhibitors of the p53–DM2 Protein–Protein Interaction

Stephen M.G Knight, Naoki Umezawa, Hee‐Seung Lee et al. · Analytical Biochemistry · 2002 · 35 citations

, , +10